Monosialotetrahexosylganglioside Sodium (GM1) roro poaka (37758-47-7)

Kia 28, 2019
SKU: 37758-47-7

Kua whakamahia te puehu GM1 ki te hamani i te hypoxic-neonatal-hechemic brain injury, te mate a Parkinson ... ..


tūnga: I roto i te Production Production
Whakaritea me te Whakaritenga Waea
Raukaha: 1277kg / marama

Monosialotetrahexosylganglioside Sodium (GM1) roro poaka (37758-47-7) ataata

Monosialotetrahexosylganglioside Sodium (GM1) roro poaka (37758-47-7) Whakaahuatanga

Monosialotetrahexosylganglioside Sodium (GM1) roro poaka (37758-47-7), ko te ingoa poto ka taea te GM1, ka tangohia mai i te roro poaka, me te mema o te raupapa o te kaiora i te wahanga o te piatara.

Ka taea e GMl te whakatairanga i te whakaora i te mahi neuroro i muri i te whara o te punaha o te pokapū o te nuinga o nga take, te whakatairanga i te neuroplasticity. Ko nga whakamatautau e whakaatu ana i te whara o te roro o te GMl, ko te roro o te mate ki te whakaora i nga kamera tawhito i roto i te whara o te raiona, he parenga whakamarumaru me te whakatairanga i te mahi o te pūtau.

I whakaatuhia te whakamatautau haumanga o mua II, ka whakaiti i te neurotoxicity oxaliplatin (ININ). Engari kihai i whakamanahia e te waahanga III. Ko te whakamātautau III e hiahiatia ana hei tirotiro i te painga me te haumaru o te monosialotetrahexosylganglioside o te konutai Soda mo te aukati i te mate pukupuku.

Monosialotetrahexosylganglioside Sodium (GM1) roro poaka (37758-47-7) SpecifiTuhinga

ingoa hua Monosialotetrahexosylganglioside Sodium (GM1) roro poaka
Ingoa Toi Monosialotetrahexosylganglioside Sodium (Poraka Porc)

Ko GM1 ranei

raupapa /
Brand Name Shenjie
Kaupapa Drug Tuhinga o mua
CAS Tau 37758-47-7
INCHIKey GTTLZSUWCRJZRC-CRQBLQEMSA-N
rāpoi FTuhinga C73H134N4O31
rāpoi Wwaru 1563.85
Ko te Monoisotopic Mass 1563.85
Te whakarewa Phinu N / He
Hawhe-Haiao-Ora /
Tae Te paura kua paheke-te-ma
memehatanga chloroform / methanol (9: 1): 10 mg / mL, maamaa, taekore
Storage Tte taumaha -20 ° C
Apātai He kaiwhakaatu motuhake mo te toxin cholera e kohikohi ana i roto i te roro i te mutunga o te lipidosis.
Te whakamatautau i nga mea I roto i te Whare Kounga Paerewa
Character Te paura ma te maama; paku iti, te reka; makuku. Ko tenei hua he wairewa i roto i te wai, he iti rawa te rewa i roto i te methanol, kaore i te kuhu i te waihanga anhydrous.
Tāutunga
Whakaaho i te tauhohenga 1 Tangohia te 0.2ml waihanga whakamatautau i raro i te whakataunga o te ihirangi, me te whakauru i te wai 2ml, me te whakauru i te waikawa waikawa waikawa hydrohydrate (hydroquinone 0.2g, te whakakore i te wai 10ml waipiro, te whakauru 90ml waikawa waikawa, te 0.1mol / L Copper sulfate solution 0.25ml, te tiaki i te pouaka) 2ml, te horoi wai horoi mo nga meneti 15, te wairewa puru me te papura, me te waipiro o te waipiro waipiro 5ml, kaore te waipiro waipiro he puru.
Whakaaho i te tauhohenga 2 Tangohia tenei hua e pā ana ki 20mg, tāpirihia te 1ml waikawa waikawa, te wai wera wai wera katoa, kia toru atu nga pata o te wairewa 1, i roto i te wairere wera i te taiepa o te ngongo ka āta whakapirihia te waipiro sulfuric 1ml, kia rua nga papahanga , kia parauri te tautuhinga piti-wai
Te tote konutai Ko te urupare tautuhi o te tote konutai i roto i tenei hua (ko te putanga 2015 te Chinese Pharmacopoeia 0301).
Ko te chromatography waipiro (LC) I roto i te kauwhata a te kiriata i tuhia i raro i te whakataunga o te ihirangi, me rite te wa pupuri mo te otinga matua o te otinga whakamatautau me te wa pupuri o te pito matua o te otinga whakahaere.
Haupae rererangi purapura Ko te mahere whakauru maramarama o tenei hua kia rite ki te mahere o te hua whakahaere (ko te putanga 2015 o te Chinese Pharmacopoeia 0402).
Tirohia
PH 5.0 ~ 6.5
Te marama me te tae o te otinga Me whakamarama te taekore; ki te mea he kapua, kaore e nui atu i te wai paerewa o te raruraru Nama 1th; Mena ka kore te tae o te tae e hohonu atu i te otinga tae o te Nama Nama 1th.
Te Whakariterite Teitei Ko te otinga kua oti te whakaoti kia marama me te whai kiko i muri i te teitei teitei, kaore he waiu miraka, kaore he rereke
Te hiranga o te whakaaro (Te purongo rereke) ≤50000
Te katoa o te waikawa Sialic E ai ki te whakamahinga hua hua maroke, ko te wai o te waikawa me 19.0 ~ 21.0%
matū e pā ana Ko te waikawa Sialic ≤0.3%; GD3, GD1a, he pokekore te mohiotia ko ≤ 0.5%; kino me te ≤2.0%
pūmua ≤1.0%
He pokekore te taimaha o te taimaha ≤0.5%
Ngā whakarewa taiao Methanol ≤ 0.1%; acetone ≤ 0.3%; Trichloromethane ≤0.003%
Water ≤4.0%
Te wera o te toenga ≤5.0%
He whakarewa taimaha ≤20ppm
He mate kino rawa Ture Whakatau
Ngā matū antihypertensive Kia rite ki nga whakaritenga (maha nga waahanga whakahaere)
Pyrogen Kia rite ki nga whakaritenga (maha nga waahanga whakahaere)
Nga waahanga umanga Ko te tapeke o nga huaketo aukati he <100cfu / g, me te tapeke o nga mowhiti me nga reta me <50cfu / g
Taumahi ≥98.0%

raw MONOSIALOTETRAHEXOSYLGANGLIOSIDE SODIUM (GM1) puehu (37758-47-7) Whakaahuatanga

Monosialotetrahexosylganglioside Sodium (37758-47-7), ko te ingoa poto ka taea te GM1, ka tangohia mai i te roro poaka, a, he mema o te raupapa o te kaiora o te tipu o te kaiao e whai ana i tetahi atu waikawa sialic.

Ka taea e GM1 te whakaoho i te whakaora i te mahi neuroro i muri i te whara o te pünaha o te pokapū matua o te tini o nga take, te whakatairanga i te neuroplasticity. Ko nga whakamatautau e whakaatu ana i te whara o te roro o te GM1, te mate o te mate ki te whakaora i nga kamera nerve i roto i te whara o te raiona, he mea whakamarumaru me te whakatairanga i te mahi o te pūtau.

I whakaatuhia te whakamatautau haumanga o mua II, ka whakaiti i te neurotoxicity oxaliplatin (ININ). Engari kihai i whakamanahia e te waahanga III. Ko te whakamātautau III e hiahiatia ana hei tirotiro i te painga me te haumaru o te monosialotetrahexosylganglioside o te konutai Soda mo te aukati i te mate pukupuku.

MONOSIALOTETRAHEXOSYLGANGLIOSIDE SODIUM (GM1) puehu (37758-47-7) Te mahi o nga mahi?

GM1 (monosialotetrahexosylganglioside) te "prototype" ganglioside, he mema o te raupapa ganglio o nga gangliosides kei roto i tetahi atu waikawa sialic. Kei te GM1 nga āhuatanga hauora o te mate me te painga ki te hangarau kiriuinga me te hangarau, me te tuku i nga neurotrophins i roto i te roro. I tua atu i tana mahi i roto i te hangarau o te roro, ka mahi a GM1 hei pae honohono mo te cholera toxin me E. coli te wera-labile enterotoxin.

painga of MONOSIALOTETRAHEXOSYLGANGLIOSIDE SODIUM (GM1) puehu (37758-47-7)

Ko Ganglioside GM1 he mema o te hapu ganglioside i whakamahia i roto i nga whenua maha, a ko te whakaaro he maimoatanga rereke mo te aukati i te maha o nga mate taiao, tae atu ki te whara o te mate. Ko nga hua rongoā o te GM1 kua whakamatauhia i roto i nga waahi me nga pakeke i muri i te mate o te roro.

tūtohu MONOSIALOTETRAHEXOSYLGANGLIOSIDE SODIUM (GM1) puehu (37758-47-7) Tauranga

I whakahaeretia te Drug i te horopeta o te 20-40 mg i ia ra, ma te whakamahi i te urutomo o te rorohiko me te ngawari ranei i runga i nga tohutohu a te taote. I roto i te waahi whakaheke o te huringa pathological: I whakamahia te rongoā i te horopeta o te 100 mg i ia ra, ma te wero taiao; I muri i nga wiki 2-3, ka mau tonu te nui o te 20-40 mg i ia ra mo nga wiki e ono, ko te horopato tuatahi o te 500-1000 mg i whakahaeretia e te pupuhi kino mo te mate o Parkinson; mai i te ra tuarua, ka whakamahia te tarukino me te horopeta o te 200 mg i ia ra, i te taha o te taraiwa, te urutanga intramuscular ranei te pungarehu mo nga wiki 18. i te wa e whakahaerehia ana tenei tarukino e te Ngatahanga o te taraiwa, o te wero ranei, ka whakakorea, ka werohia i roto i te wai mo te werohanga kia tae noa ki te kukume o 10 mg / ml i te; i te wa e kino ana te waipiro, ka tohaina te tarukino me te diluted i te 0.9% te konutai ngota konupuku ranei 5% te wero o te huka.

pānga taha of MONOSIALOTETRAHEXOSYLGANGLIOSIDE SODIUM (GM1) puehu (37758-47-7)

Ko te painga o te pauna o GM1 ko te nuinga o te urupare kaore i te whakamahia.

TE WHAKAMAHI ME TE KAUPAPA:

E Hokona ana tenei Pae Hei Whakamahi Rangahau anake. Tikanga o te Hoko Tono. Ehara i te mea mo te Tangata a te Tangata, kaore i te Akutaina, Whaiao, Whare Whainga Kaainga ranei.