Dihydromyricetin (DHM) (27200-12-0)

March 9, 2020

Ko te Dihydromyricetin (ko DHM ranei) he tangohanga mai i te Raisin Tree Japanese e whakamahia ana mo nga rau tau hei anti-waipiro …….


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Whakaritea me te Whakaritenga Waea
Raukaha: 1277kg / marama

Ataata dihydromyricetin (DHM) (27200-12-0) ataata

Pepa Hauora Snga whakaritenga

ingoa hua Dihydromyricetin (DHM)
Ingoa Toi Ampelopsin
Ampeloptin
(+) - Dihydromyricetin
ingoa Brand N / He
Kaupapa Drug phytochemical; paerewa tohutoro mai i nga otaota rongoa Hainamana (TCM); tangohanga otaota paerewa; hua taiao; Inhibitors; Flavanones; reagent matū;
CAS Tau 27200-12-0
INCHIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
rāpoi FTuhinga C15H12O8
rāpoi Wwaru 320.25 g / mol
Ko te Monoisotopic Mass 320.053217 g / mol
wāhi e koropupu ana 780.7 ± 60.0 ° C (Matapae)
Fwhakahou Phinu N / He
Hawhe-Haiao-Ora N / He
Tae he ma ki te piupiu
STuhinga DMSO: ≥5mg / mL (mahana)
Stora Tte taumaha <+ 8 ° C
Apātai 1. Ka whakamahia i roto i te umanga kai, ko te paura dihydromyricetin hei rauemi mata;
2. Kua whakauruhia ki roto i te hua hauora, te paura dihydromyricetin hei rauemi taapiri hei whakatairanga i te tuakiri o te tinana;
3. Kua whakauruhia ki roto i te mara rongoā, te paura tango dihydromyricetin hei whakamahinga ki te kapi, i te paariki ranei hei rongoa i te mate urupare me te tiaki i te ate.

History History Dihydromyricetin

Ko te Dihydromyricetin (ko DHM) he tangohanga mai i te Raisin Tree Japanese e whakamahia ana mo nga rau tau hei raau haumi haurangi me te rongoa hangover i Korea me te rongoa tuku iho a Hainamana. Ko nga rangahau o mua i kii ko te DHM ka taea te whakaheke i te taumata waipiro toto me te tiaki i o ate ki te kino me te mate.

Ko te DHM he flavonoid tino tangohia i te Tomo waina engari ka taea hoki te tango mai i te kiri o te rakau Holvenia Dulcis. A ko te mea tino nui, he roa nga korero o Dihydromyricetin mo te kaupapa o te rongoa i nga makawe me nga hangovers.

He aha te Dihydromyricetin?

Ko te dihydromyricetin, he mohio ano ko Ampelopsin, he flavanonol, he momo flavonoid. Ka kitea i roto i te momo Ampelopsis japonica, megalophylla, me grossedentata; Cercidiphyllum japonicum; Hovenia dulcis; Rhododendron cinnabarinum; etahi momo Pinus; ko etahi Cedrus momo, me i Salix sachalinensis.

Ko te paura tangohanga a te dihydromyricetin, ko te whakauru kaha ko te flavonoids. Na nga mahi o te haehae haruru kore, antioxidants, antithrombotic, Tumor, anti-inflammatory me etahi atu mea rereke; Ko te Dihydromyricetin he pūhui flavonoid motuhake. Hei taapiri atu i nga tikanga whanui o te flavonoids, ka taea hoki te whakamamae i te paitini waipiro, te aukati i te haurangi, te ngako momona, me te aukati i nga pūtau ate. Te whakawhiwhi me te whakaheke i te mate pukupuku o te ate. He hua pai mo te tiaki i te ate me te hangover.

Pepa Hauora painga

NGĀ WHAKAMAHI KAUPAPA ANTI-HANGOVER

Ko te painga matua o te DHM ko te aukati me te whakaiti i nga hangovers, hei tiaki i to ate me to roro. Ko tenei ka whakatutukihia e te whakarei ake i te waipiro o te dehydrogenase (ADH) me te acetaldehyde dehydrogenase (ALDH), koinei nga wharepukapuka matua e haangai ana ki te wawahi i te waipiro me te acetaldehyde i roto i te tinana.

Ko te Acetaldehyde he matū tino paitini me tetahi o nga take nui o te hangovers. Mena ka whakareihia ake nga enomea, ka taea te pakaru o te waipiro me te acetaldehyde tere atu i te waa.

Tuhinga o mua

He maha nga waahanga hauora hauora a DHM e tuku moni ana ki a raatau ki te whakatairanga i te hauora hinengaro. Ka puta mai tenei na te mea ka whakatairanga a DHM i te heme-oxygenase-1 (HO-1), he enzim e whakaohooho ana i te ngoikore o te heme me te whakawhiwhi i nga waahanga hauora. Ka taea hoki e te dihydromyricetin te whakatairanga i te hauora o te ate.

Ko etahi atu ko te dihydromyricetin te painga

1) Ka taea e te dihydromyricetin te horoi i nga mahi koretake i roto i te tinana me te antioxidation

2) Ka taea e te dihydromyricetin te Mahi Antibiotic

3) Ka taea e te Dihydromyricetin te Tiaki i te Hopu: He kaha te aukati i te Dihydromyricetin i te pikinga o te ALT me te AST i roto i te toto Serum. Ka taea e ia te whakaheke i te bilirubin katoa i roto i te serum toto. No reira he kaha te mahi ki te whakaheke i te aminotransferase me te jaundice.

4) Ka taea e te dihydromyricetin te whakaiti i nga taumata o te huka toto me te hinu toto: Dihydromyricetin ka taea te whakaheke i nga taumata momona toto i roto i nga kiore. Ka taea te whakaheke i te whara o nga pūtau ate e hua ana i te taumata momona toto nui me te whakapai ake i te kaha antioxidation. I te wa ano, ka taea e ia te whakaheke i te taumata o te huka toto nui.

5) Ka taea te Dihydromyricetin te Whakakorekore

6) Ka taea e te dihydromyricetin te whakaeke i te puku-puku: Ko te paura tangutuna o te tangihoki ka taea te aukati i te tipu o etahi pūtau puku.

Nga waahanga taha o te dihydromyricetin.

I roto i te nuinga he iti noa nga rangahau ki te titiro ki nga tohu taha o te taha DHMs a tae noa ki tenei kaore ano he raru e raru.

Ko te rapu tere i runga i Amazon ka whakaatu i nga mano o nga arotake. Ma te tirotiro haere i a raatau, etahi ripoata mo te mamae o te kopu, te whakapairuaki, me te tupapo. Heoi, kaore i te maha o nga kaihoko e ripoata ana i enei paanga.

Te whakamahi me te tono a Dihydromyricetin

Whakamahinga:

  1. Ko te paura Dihydromyricetin e whakamahia ana hei tiaki i te ate;
  2. Ko te paura Dihydromyricetin e whakamahia ana hei whakahaere i te momona huka toto;
  3. Ko te paura Dihydromyricetin kua whai mana ki te whakarei ake i te mate tahuma o te tinana;
  4. Ko te paura Dihydromyricetin me te mahi o te antioxidant me te anti-mate pukupuku;
  5. Ko te paura Dihydromyricetin e whakamahia ana mo te mate antio, te maimoatanga i te mare, te mamae me te whakakore i te paowa paowa.
  6. Ko te dihydromyricetin te tumanako ki te whakawhanaketanga o nga hua tiaki kiri-raau raau taero ranei mo te aukati me te rongoa i nga whara kiri.

Taupānga

  1. I whakamahia i roto i te umanga kai, ko te paura dihydromyricetin hei rauemi mata;
  2. Kua whakauruhia ki roto i te hua hauora, te paura dihydromyricetin hei rauemi taapiri hei whakarei ake i te mate tuuturu;
  3. Ka whakauruhia ki roto i te mara rongoā, te paura tango dihydromyricetin hei whakamahinga ki te kapi, ki te paera ranei ki te hamani i te mate urupare kiki me te tiaki i te ate.

Pepa Hauora rangahau in Anti-Hauora

Ina hoki, kei reira etahi rangahau tino kaha e whakaatu ana kei te kaha te awhina o te dihydromyricetin ki te kaupapa kore haurangi e pa ana ki te Hepatocellular carcinoma (HCC). Ko te HCC he tikanga e whakaatu ana i tetahi o nga mamae kino o te morbidity me te tahuti mate huri noa i te ao, me te whakaatu i te mana nui o te mate pukupuku ate tuatahi. I te mea e whakaatu ana te DHM he kaha tiaki i te ate (he hepatepototika) i puta mai nga hua i kaha ai te aukati i te tipu o te pūtau me te apoptosis e whakauruhia ana i roto i nga raina pūtau HCC, e tohu ana ko te DHM he kaitono whakaari mo te maimoatanga o te HCC.

tohutoro:

Ko te dihydromyricetin te whakaahuru i te cardiotoxicity-whakaawe i te doxorubicin ma te aukati i te mumula NLRP3 ma te whakahohe i te SIRT1. Sun Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H. Biochem Pharmacol. 2020 Pepuere 26: 113888. doi: 10.1016 / j.bcp.2020.113888. [Epub Tuhinga o mua]

Ko te Metabolomics o te Maakete Haumaru o te Ampelopsis grossedentata me tana Tinana Meiha Huatahi Dihydromyricetin i te Liver of High-Fat Diet Hamster. Fan L, Qu X, Yi T, Peng Y, Jiang M, Miao J, Xiao P. Evid Based Complement Alternat Med. 2020 Jan 28; 2020: 3472578. doi: 10.1155 / 2020/3472578. eCollection 2020.

Te ture o te haina i nga ara e Ampelopsin (Dihydromyricetin) i nga mate pukupuku rereke: te torotoro i nga huarahi me nga huarahi iti te haere. Fayyaz S, Qureshi MZ, Alhewairini SS, Avnioglu S, Attar R, Sabitaliyevich UY, Buha A, Salahuddin H, Adylova A, Tahir F, Pawlak-Adamska E. Cell Mol Biol (Noisy-le-grand). 2019 Sep 30; 65 (7): 15-20.

Ko te whakahiato o te Golgi me te whakakao i te pūmua 65 te whakaheke i te pūmua XNUMX mo te paanga anti-mate pukupuku o te dihydromyricetin i nga pūtau mate pukupuku i roto i te tangata. Wang F, Chen X, Yuan D, Yi Y, Luo Y.

Piko Tuarua. 2019 Nov 26; 14 (11): e0225450. doi: 10.1371 / journal.pone.0225450. eCollection 2019.

TE WHAKAMAHI ME TE KAUPAPA:

E Hokona ana tenei Pae Hei Whakamahi Rangahau anake. Tikanga o te Hoko Tono. Ehara i te mea mo te Tangata a te Tangata, kaore i te Akutaina, Whaiao, Whare Whainga Kaainga ranei.