Nicotinamide Mononucleotide (NMN) (1094-61-7)

Nicotinamide Mononucleotide (NMN) (1094-61-7) ataata

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

Raw Nicotinamide Mononucleotide puehu ("NMN" me "β-NMN") he nucleotide i puta mai i te ribose me te nicotinamide. Ka rite ki te riboside nicotinamide, Ko te NMN he painga o te niacin, a ko nga tangata he maurau e taea ai te whakamahi i te NMN hei whakaputa i te adinine dinucleotide (NADH) nicotinamide.

No te mea ko te NADH he kaitautoko mo nga tukanga i roto i te mitochondria, mo nga rangatira, mo te PARP, kua whakaakona a NMN i nga tauira kararehe kia rite ki te neuroprotective me te kaitohutohu pakeke. Ko nga kamupene whakauru kaihoko kua kaha te hokohoko i nga hua NMN e kii ana i aua painga, ahakoa kaore he rangahau haumanu i te tangata i whakaputaina.

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

Raw Nicotinamide Mononucleotide puehu ("NMN" me "β-NMN") he nucleotide i puta mai i te ribose me te nicotinamide. Ka rite ki te riboside nicotinamide, Ko te NMN he painga o te niacin, a ko nga tangata he maurau e taea ai te whakamahi i te NMN hei whakaputa i te adinine dinucleotide (NADH) nicotinamide.

Ko nga rangahau hou e tohu ana kia whakahokia mai e te NMN te whakawhitinga o te taiao, me te whai hua nui o te paari. Ko te tikanga o te tinana, ko te NMN (β-Nicotinamide mononucleotide) he mea nui mo te whakahuri o nga matūkai ki te kaha. Ko te whakarahi i te NMN hei waahanga o taau whakahaere i ia ra, ka taea te whakaora i te kaha, te tiaki i te tukanga tawhito, me te whakaiti i te raruraru o nga raruraru a-hinengaro. Ko te NMN he kaihautu i roto i nga hohenga redox, he tukanga nui ki te mahi taiao i roto i te hanganga o ATP te kamupene teitei-kaha. Kei roto i te NMN he pühui whakahoahoa Sirtuin e whakatairanga ana i te tika me te waatea.

Te whakamahi o Nicotinamide Mononucleotide (NMN) puehu (1094-61-7)

1. Ko te mononucleotide Nicotinamide i roto i nga ruma o te tangata e whai wāhi nui ana i roto i te whanaketanga kaha, kei te whai i roto i te NAD intracellularular (te koiora-adinine dinucleotide, te whakawhitinga pūngao whakawhitinga urupare nui), te whakamahi i te pakeke, te huka toto me etahi atu hua tiaki hauora.
2. Ko Nicotinamide Mononucleotide he waiora wairewa-wai, Ko te hua he maama tioata tioata, he mea korekore, he kore noa ranei, he kawa i roto i te reka, he wairewa noa i roto i te wai, i te waikawa ranei, e tuwhera ana i te glycerin.
3. Ko te Nicotinamide Mononucleotidepowderis he ngawari ki te hopu i te waha, me te wehewehea i roto i te tinana, ka tere te tango atu i te waikawa me te tauira i te urine. Ko Nicotinamide tetahi wahi o te coenzyme I me te coenzyme II e mahi ana i te tukunga hauora i roto i te kohinga ngongo hiko o te koiora, ka taea te whakatairanga i te tukanga pitihāora o te koiora me te hanganga o te tinana, te pupuri i te kiko o te tinana (ina koa te kiri, te kirutiri me te taiao kapi) he mea nui.

I tua atu, ko te nicotinamide he maimoatanga me te maimoatanga o te poraka o te ngakau, te mahi node hara, me te arrhythmias whakamatautau rapanga, ka taea e te nicotinamide te whakapai ake i te auau o te ngakau, me te poraka o-te-a-te-poraka e tukuna ana e nga kamera.

painga Tuhinga o mua (NMN) puehu (1094-61-7)

• Ma te NMN e whakanui te kaha o te kaha - Ko te NAD + ka awhina i te tohatoha i nga kai penei i te huka ki te kaha.
• Whakapai i te Hauora Hauora me te Mahi Cardiovascular.
• Te Whakatika i te DNA Anti-Aging - Ka whakamahia te NAD + hei whakapai i nga whenu DNA pakaru.
• SIRTUIN Whakahohe - NAD + e hiahiatia ana kia pai te mahi o o taatau ira.
• Ko te NMN te puna i whakamahia e te Harvard Scientists ki te whakakore i etahi tohu o te kiko tawhito i roto i nga kiore i timata i te tere ki nga whakawhitinga NAD.
• Ko te maimoatanga NMN ka awhina i te whara o te roro i te cICH
• Ma te NMN e whakaora i nga mate kino
• Ma te Nicotinamide mononucleotide e whakakore i te whakahoaetanga a JNK hei whakakore i te mate Alzheimer
• Ka taea e te NMN te whakahoki i te ako i roto i nga kiore tauira AD

I taunakihia a Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Tauranga

Ko te nuinga o te waahana o Nicotinamide Mononucleotide te paura i waenganui i te 250 - 1500 mg i ia ra.

Ko te NMN kua tino tere, kua roa te ora, kia mau tonu nga taumata NAD + mo te nui o te ra ka taea te tango i tetahi kapene 125 mg i te oho me tetahi atu i te ahiahi ka tango i te 250 mg i ia ra.

pānga taha Tuhinga o mua (NMN) puehu (1094-61-7)

Ahakoa ko te paura Nicotinamide mononucleotide (NMN) te paura he taapiringa hou, kei te haere tonu nga rangahau, ko nga rangahau i mahia i tenei wa kua whakaatuhia he tino ahuru me te kore paitini.

Kaore nga paanga o te taangata e tupono, engari ko te waatea, te ngawari, te wera, me te tausea kua whakaaturia i etahi waa.

Tohutoro

1. Nina Klimova, Tibor Kristian. Pānga Maha-whaaia o Nicotinamide Mononucleotide mo te Brain Bioenergetic Metabolism. Neurochem Res. 2019 Oketopa; 44 (10): 2280-2287. mahi: 10.1007 / s11064-019-02729-0.PMID: 30661231.
2. Aaron N Long, Katrina Owens, Anna E Schlappal, Tibor Kristian, Paul S Fishman, Rosemary A Schuh. Nga painga o te monotucleamide nikotinamide i runga i nga ngoikoretanga o te manawa mitochondrial roro i roto i te tauira murine e pa ana ki te mate a Alzheimer. BMC Neurol. 2015 Maehe 1; 15:19. mahi: 10.1186 / s12883-015-0272-x.PMID: 25884176.
3. Ji H Park, Aaron Long, Katrina Owens, Tibor Kristian. Ko te monotucleamide Nicotinamide te aukati i te whakahekenga o te NAD (+) i muri o te ischemic me te tino whakaniko i te kino o te roro e whai ake nei Neurobiol Dis. 2016 Whiringa; 95: 102-10. mahi: 10.1016 / j.nbd.2016.07.018. Epub 2016 Jul 15. PMID: 27425894, PMCID: PMC558024.
4. Junichiro Irie, Hiroshi Itoh. Te koroheketanga me te homeostasis. Nga mate e pa ana ki te tau me te whakamahinga haumanu o te NMN (Nicotinamide Mononucleotide). Clin Calcium. 2017; 27 (7): 983-990. PMID: 28649105.
5. Golam Mezbah Uddin, Neil A Youngson, Bronte M Doyle, David A Sinclair, Margaret J Morris. Ko te taapiringa a te Nicotinamide mononucleotide (NMN) te whakanui i te paanga o te momona o te whaea ki nga kiore: te whakataurite me te korikori Sci Rep. 2017 Nov 8; 7 (1): 15063. mahi: 10.1038 / s41598-017-14866-z. PMID: 29118320, PMCID: PMC5678092.
6. Nga tarukino whakakino hou-anti-Aging: Nicotinamide Mononucleotide (NMN)