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Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7)

Raw Nicotinamide Mononucleotide (NMN) te paura e pa ana te taimaha o te tinana e pa ana ...


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Whakaahuatanga

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) ataata

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

Raw Nicotinamide Mononucleotide puehu ("NMN" me "β-NMN") he nucleotide i puta mai i te ribose me te nicotinamide. Ka rite ki te riboside nicotinamide, Ko te NMN he painga o te niacin, a ko nga tangata he maurau e taea ai te whakamahi i te NMN hei whakaputa i te adinine dinucleotide (NADH) nicotinamide.

No te mea ko te NADH he kaitautoko mo nga tukanga i roto i te mitochondria, mo nga rangatira, mo te PARP, kua whakaakona a NMN i nga tauira kararehe kia rite ki te neuroprotective me te kaitohutohu pakeke. Ko nga kamupene whakauru kaihoko kua kaha te hokohoko i nga hua NMN e kii ana i aua painga, ahakoa kaore he rangahau haumanu i te tangata i whakaputaina.

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

ingoa hua Rawa Nicotinamide Mononucleotide (NMN) puehu
Ingoa Toi Te monophosphate beta-nicotinamide ribose; Raw Nicotinamide Mononucleotide puehu; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
Brand Name Mirailabo
Kaupapa Drug Kaihautanga kai
CAS Tau 1094-61-7
INCHIKey DAYLJWODMCOQEW-TURQNECASA-N
rāpoi FTuhinga C11H15N2O8P
rāpoi Wwaru 334.22
Ko te Monoisotopic Mass 335.229 g / mol
Te whakarewa Phinu > 96 ° C
Fwhakahou Phinu Kāore he ra e wātea ana
Hawhe-Haiao-Ora Na, i te mea i whakaaturia i te Fig. 3, ngaro te nicotinamide i te toto me te haurua o nga haora 5.3, ko te hawhe o te ora o te waikawa nicotinic he 1.1 haora.
Tae White ki te paura ma-paura
STuhinga Methanol (Maama), Te wai (Taku)
Stora Tte taumaha Hygroscopic, -20˚C Kaihauturu, I raro i te Inmosphere
Apātai Hei mahi i te mahi o te roa o te ora me te maimoatanga o te mate huka

Raw Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Whakaahuatanga

Raw Nicotinamide Mononucleotide puehu ("NMN" me "β-NMN") he nucleotide i puta mai i te ribose me te nicotinamide. Ka rite ki te riboside nicotinamide, Ko te NMN he painga o te niacin, a ko nga tangata he maurau e taea ai te whakamahi i te NMN hei whakaputa i te adinine dinucleotide (NADH) nicotinamide.

Ko nga rangahau hou e tohu ana kia whakahokia mai e te NMN te whakawhitinga o te taiao, me te whai hua nui o te paari. Ko te tikanga o te tinana, ko te NMN (β-Nicotinamide mononucleotide) he mea nui mo te whakahuri o nga matūkai ki te kaha. Ko te whakarahi i te NMN hei waahanga o taau whakahaere i ia ra, ka taea te whakaora i te kaha, te tiaki i te tukanga tawhito, me te whakaiti i te raruraru o nga raruraru a-hinengaro. Ko te NMN he kaihautu i roto i nga hohenga redox, he tukanga nui ki te mahi taiao i roto i te hanganga o ATP te kamupene teitei-kaha. Kei roto i te NMN he pühui whakahoahoa Sirtuin e whakatairanga ana i te tika me te waatea.

Te whakamahi o Nicotinamide Mononucleotide (NMN) puehu (1094-61-7)

  1. Ko te mononucleotide Nicotinamide i roto i nga ruma o te tangata e whai wāhi nui ana i roto i te whanaketanga kaha, kei te whai i roto i te NAD intracellularular (te koiora-adinine dinucleotide, te whakawhitinga pūngao whakawhitinga urupare nui), te whakamahi i te pakeke, te huka toto me etahi atu hua tiaki hauora.
  2. Ko Nicotinamide Mononucleotide he waiora wairewa-wai, Ko te hua he maama tioata tioata, he mea korekore, he kore noa ranei, he kawa i roto i te reka, he wairewa noa i roto i te wai, i te waikawa ranei, e tuwhera ana i te glycerin.
  3. Ko te Nicotinamide Mononucleotidepowderis he ngawari ki te hopu i te waha, me te wehewehea i roto i te tinana, ka tere te tango atu i te waikawa me te tauira i te urine. Ko Nicotinamide tetahi wahi o te coenzyme I me te coenzyme II e mahi ana i te tukunga hauora i roto i te kohinga ngongo hiko o te koiora, ka taea te whakatairanga i te tukanga pitihāora o te koiora me te hanganga o te tinana, te pupuri i te kiko o te tinana (ina koa te kiri, te kirutiri me te taiao kapi) he mea nui.

I tua atu, ko te nicotinamide he maimoatanga me te maimoatanga o te poraka o te ngakau, te mahi node hara, me te arrhythmias whakamatautau rapanga, ka taea e te nicotinamide te whakapai ake i te auau o te ngakau, me te poraka o-te-a-te-poraka e tukuna ana e nga kamera.

painga Tuhinga o mua (NMN) puehu (1094-61-7)

  • Nö te NMN e hanga ana i te Energy Metabolism - Ka awhina a NAD + ki te whakaheke i te kai hei kai ki te kaha.
  • Whakapai i te Hauora Hauora me te Mahi Cardiovascular.
  • Ko te Whakaoho DNA-Aging-Aging - E whakamahia ana a NAD + ki te hanga i nga whenu DNA pakaru.
  • NGÄ KAUPAPA KAI - Ko te NAD + e hiahiatia ana mo o taatau pikinga roa ki te mahi.
  • Ko te NMN te puna i whakamahia e te Harvard Scientists ki te whakakore i etahi tohu o te kiko tawhito i roto i nga kiore i timata i te tere ki nga whakawhitinga NAD.
  • Ko te maimoatanga NMN ka awhina i te whara o te roro i te cICH
  • Ma te NMN e whakaora i nga mate kino
  • Ma te Nicotinamide mononucleotide e whakakore i te whakahoaetanga a JNK hei whakakore i te mate Alzheimer
  • Ka taea e te NMN te whakahoki i te ako i roto i nga kiore tauira AD

I taunakihia a Nicotinamide Mononucleotide (NMN) puehu (1094-61-7) Tauranga

Ko te nuinga o te waahana o Nicotinamide Mononucleotide te paura i waenganui i te 250 - 1500 mg i ia ra.

Ko te NMN kua tino tere, kua roa te ora, kia mau tonu nga taumata NAD + mo te nui o te ra ka taea te tango i tetahi kapene 125 mg i te oho me tetahi atu i te ahiahi ka tango i te 250 mg i ia ra.

pānga taha Tuhinga o mua (NMN) puehu (1094-61-7)

Ahakoa ko te puehu o Nicotinamide mononucleotide (NMN) he kohinga hou me te rangahau tonu kei te haere tonu, ko nga rangahau kua whakaatuhia i tenei wa kua whakaatuhia kia noho haumaru, kaore hoki e paowa.

Kaore nga paanga o te taangata e tupono, engari ko te waatea, te ngawari, te wera, me te tausea kua whakaaturia i etahi waa.

TE WHAKAMAHI ME TE KAUPAPA:

E Hokona ana tenei Pae Hei Whakamahi Rangahau anake. Tikanga o te Hoko Tono. Ehara i te mea mo te Tangata a te Tangata, kaore i te Akutaina, Whaiao, Whare Whainga Kaainga ranei.


Ngā tohutoro me nga whakautu hua

2019 Nga Tohunga Taoho Ngati Hou: Ko Nicotinamide Mononucleotide (NMN)

Tohutoro

  1. Mills, KF, Yoshino, J., Yoshida, S., et al. (2016). Ko te Whakahaere Maatau-roa o Nicotinamide Mononucleotide Mitigates Ko te Tikanga Aromatawai-Taurangi-Taurangi i te Mice. Pūtaiao Pūtau.
  2. Yoshino, J., Mills, KF, Imai, SI, me Yoon, MJ (2011). Ko Nicotinamide Mononucleotide, he NAD + Intermediate, e mahi ana i te Pathophysiology o te Mate Motuhake-me te Tangata-Motuhake i te Maama. Pūtaiao Pūtau.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., me Sadoshima, J. (2014). Ko Nicotinamide Mononucleotide, he Intermediate o NAD + Synthesis, Te Tiaki i te Heart mai i te Ischemia me te Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, me Morris, MJ (2016). He upoko ki te Whakatau Peke o te Maimoatanga Poto-roa me te NAD + o mua Nicotinamide Mononucleotide (NMN) me nga wiki e ono o te Mahi i roto i te Kiore wahine.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Ko te Slc12a8 he kaihokohoko Nicotinamide Mononucleotide. Nature Metabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (2016). Ko te Nicotinamide Mononucleotide Reverses Rehabilitation Vascular and stressing Oxidative with Mice Mice.
  7. Yao, Z., Gao, Z., Yang, W., me Jia, P. (2017). Ko te Nicotinamide Mononucleotide ka aukati i te JNK Whakahohe ki te Ngaro Alzheimer Disease.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). NAD + Te Whakaritea Whakaritea i nga Mahinga Alzheimer Matua me nga Raraunga Damage a DNA i roto i te Tauira Mii Hou o te Mii me te Raraunga Aapuku DNA kua tohua.