Ko te waikawa o te waikawa o te phenethyl ester (Caffeic acid) (104594-70-9)

Hakihea 28, 2018
SKU: 104594-70-9

Ko te paura waikawa phenethyl ester waikawa raw te waikawa waipiro phenethyl o te waikawa kawhe me te koiora …… ..


tūnga: I roto i te Production Production
Waea: 25kg / Drum
Raukaha: 1180kg / marama

Ko te waipiro o te waikawa o te phenéthyl ester (104594-70-9)

 

Ko te waikawa o te waikawa o te phenethyl ester (Caffeic acid) (104594-70-9) Snga whakaritenga

ingoa hua Te waikawa o te waikawa o te waipiro phenethyl ester Raw
Ingoa Toi Te waikawa o te waikawa koroni phenethyl ester;

Te caffeate Phenylethyl; Te caffeate Phenethyl; Ko te waikawa taiao 2-phenylethyl; β-Phenylethyl caffeate;

2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate

Brand Name Kaore he raraunga hei wātea
Kaupapa Drug Nga Kaipupuri Kaihauturu o Tyrosine, Kaiwhiwhi
CAS Tau 104594-70-9
INCHIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
rāpoi FTuhinga C17H16O4
rāpoi Wwaru 284.311 g / mol
Ko te Monoisotopic Mass 284.31 g · mol-1
Te whakarewa Phinu  125-126ºC (dec.)
wāhi e koropupu ana 498.6 ± 45.0 ° C i 760 mmHg
Hawhe-Haiao-Ora Kāore he Raraunga e wātea
Tae atu-ma
STuhinga  He ngoikore ki te acetate ethyl i 50mg / ml. He ngoikore i te DMSO me te anhanol.
Stora Tte taumaha  Tiakina i 0 ° C
Raw Kaitawai waikawa waikawa phenethyl ester Apātai Kaipupuku Cytotoxic mo nga raina pukupuku mate pukupuku. Ko te kaiwhakawa o te ornithine decarboxylase me te tyrosine kinase pūmua. I kitea hei kaipupuri takitahi o te take whakawhiti karihi, NF-kB. Kua whakaaturia hoki ki te tino tarai i te ara o te lipoxygenase o te waikawa o te waikawa o te arachidonic i te wa o te mumura.

 

Ko te waikawa o te waikawa phenethyl ester (Caffeic acid phenethyl ester) (104594-70-9) Whakaahuatanga

Ko te waikawa o te waipiro phenethyl ester ko te phenethyl alcohol ester o te waikawa caffeic me te mea koiora o te hive propolis honi, me nga mahi antineoplastic, cytoprotective, me nga mahi whakareatanga. I runga i te whakahaeretanga, ka whakakorea te waipiro o te waipiro o te phenethyl ester (CAPE) te Raw Caffeic (CAPE) i te whakakorenga o te tuhinga whakawhitinga karihi NF-kappa B me te whakakore i nga p70S6K me nga huarahi tohu tohu a Akt. I tua atu, ka whakakorehia e te CAPE te whakatairanga PDGF-i roto i te whakawhitinga o nga pūtau uaua ngohengohe i roto i te whakatinanatanga o te kinase kingi-a-te-moki-a-te-p38 (MAPK) me te mea hiko-aukati (HIF) -1alpha me te whai muri mai o te hehe oxygenase-1 (HO-1) .

Ko te waikawa phenethyl ester waikawa kua puta i te kii he anti-carcinogenic, he anti-mumura, me nga taonga whakatikatika. Ka aukati hoki te CAPE i te whakakotahitanga HIV-1. Ko nga ahuatanga anti-mumura i kiia na te pehanga o te ara lipoxygenase o te waikawa waikawa arachidonic na CAPE. Kua whakaatuhia hoki e nga rangahau te CAPE hei kaipupuri motuhake me te kaha ki te aukati i te whakahoatanga o te tauwehenga karihi NF kappa B, he matatini matatini hei whakahaere i te tuhinga o te DNA. Caffeic Acid Phenethylester he aukati i te ODC me te Tyrosine Kinase

Te waikawa waikawa phenethyl ester puehu (104594-70-9) Mahinga Mahi

Ko te waikawa o te phenffe ester te waipiro o te waipiro waipiro o te caffeic, ka poraka i te whakauru NF-κB i roto i te phorbol ester, ceramide, waikawa okadaic, me te waikawa hauora ma te aukati i te whakawhitinga o te p65 o te NF-κB ki te puranga. I roto i te raupapa o nga raina pūtau tumuaki, ko te phenéthethyl ester te hua o te koiora o te Caffeic me te EC50 o 1.76, 3.16, 13.7, me te 44.0 μM ki te kohi murino 26-L5, te muru B16-BL6 melanoma, te HT-1080 fibrosarcoma me te A549 huhu tangata nga raupapa waea tuhi adenocarcinoma. Ko te waikawa o te phenéthyl ester, ko te antioxidant kaha, ka kaha ki te whakaputa i ona huaketo anti-apoptotic i roto i nga ruma purapura miraka ma te whakakore i te hanganga ROS me te whakakore i te ngohe pakihi. Waihoki, ko te phenéthyl ester te caffeic acne te tohu tohu pro-inflammatory o LPS-whakaongaonga HSC, me te arotahi LPS-o te HSC ki te cytokines fibrogenic mā te aukati i te tohu NF-κB.

In vivo, Ko te waikawa o te phenéthyl ester (10 mg / kg, ip) ka whakakore i te tipu me te angiogenesis o nga pukupuku tuatahi i roto i te C57BL / 6 me te BALB / c e whakamahia ana ki te Leung o te carcinoma, te kaporeihana koroni, me nga kamera melanoma. Ko te waikawa o te phenethyl ester (5, 10, 20 mg / kg) ka whakaatu i nga hua o te immunomodulatory i roto i te ora i te whakaiti i te taimaha me te whakarau o te kaimoana me te rere.

Te whakamahinga o te waikawa waikawa phenethyl ester (Caffeic acid) (104594-70-9)

▪ Antineoplastic

▪ Aantiinflamirus

▪ Iimmunomodulator

▪ NFkB aukati

hua o Ko te waikawa waikawa phenethyl ester (Caffeic acid) (104594-70-9)

Ko te Phenethyl caffeate he pūhui ka kitea i roto i te propolis, he ranunga na te pi e whakaputa. Ka whai hua te Caffeic acid phenethyl ester (CAPE) ki te aukati me te whakamaimoa i nga mate mumura tae atu ki te mate rheumatoid, te lupus erythematosus me te psoriasis, nga momo mate pukupuku me nga mate kei roto ko te hanga puku, ngongo, me etahi atu mate i puta mai i te awangawanga o te waikura. Ano hoki, ka taea te whakamahi i te CAPE ki te whakaora i tetahi mate HIV ka whakakotahihia ki te raau rongoa me tetahi taonga e aukati ana i te taarua o te HIV. Ka taea hoki te whakamahi ki te anti-atherosclerotic, antioxidative, cardioprotective, anti-obesity me te antimitogenic.