Ko te waikawa o te waikawa o te phenethyl ester (Caffeic acid) (104594-70-9)

Hakihea 28, 2018
SKU: 104594-70-9
5.00 i roto i te 5 hāngai ana i runga i 1 whakatauranga kiritaki

Ko te waikawa o te waipiro phenethyl ester te nui o te caffeic ko te pheneryl alcohol ester o te waikawa caffeic me te koiora ...


tūnga: I roto i te Production Production
Waea: 25kg / Drum
Raukaha: 1180kg / marama

Ko te waipiro o te waikawa o te phenéthyl ester (104594-70-9)

Ko te waikawa o te waikawa o te phenethyl ester (Caffeic acid) (104594-70-9) Snga whakaritenga

ingoa hua Te waikawa o te waikawa o te waipiro phenethyl ester Raw
Ingoa Toi Te waikawa o te waikawa koroni phenethyl ester;

Te caffeate Phenylethyl; Te caffeate Phenethyl; Ko te waikawa taiao 2-phenylethyl; β-Phenylethyl caffeate;

2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate

Brand Name Kaore he raraunga hei wātea
Kaupapa Drug Nga Kaipupuri Kaihauturu o Tyrosine, Kaiwhiwhi
CAS Tau 104594-70-9
INCHIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
rāpoi FTuhinga C17H16O4
rāpoi Wwaru 284.311 g / mol
Ko te Monoisotopic Mass 284.31 g · mol-1
Te whakarewa Phinu 125-126ºC (dec.)
wāhi e koropupu ana 498.6 ± 45.0 ° C i 760 mmHg
Hawhe-Haiao-Ora Kāore he Raraunga e wātea
Tae atu-ma
STuhinga He ngoikore ki te acetate ethyl i 50mg / ml. He ngoikore i te DMSO me te anhanol.
Stora Tte taumaha Tiakina i 0 ° C
Raw Kaitawai waikawa waikawa phenethyl ester Apātai Kaipupuku Cytotoxic mo nga raina pukupuku mate pukupuku. Ko te kaiwhakawa o te ornithine decarboxylase me te tyrosine kinase pūmua. I kitea hei kaipupuri takitahi o te take whakawhiti karihi, NF-kB. Kua whakaaturia hoki ki te tino tarai i te ara o te lipoxygenase o te waikawa o te waikawa o te arachidonic i te wa o te mumura.

Ko te waikawa o te waikawa phenethyl ester (Caffeic acid phenethyl ester) (104594-70-9) Whakaahuatanga

Ko te waikawa o te waipiro phenethyl ester ko te phenethyl alcohol ester o te waikawa caffeic me te mea koiora o te hive propolis honi, me nga mahi antineoplastic, cytoprotective, me nga mahi whakareatanga. I runga i te whakahaeretanga, ka whakakorea te waipiro o te waipiro o te phenethyl ester (CAPE) te Raw Caffeic (CAPE) i te whakakorenga o te tuhinga whakawhitinga karihi NF-kappa B me te whakakore i nga p70S6K me nga huarahi tohu tohu a Akt. I tua atu, ka whakakorehia e te CAPE te whakatairanga PDGF-i roto i te whakawhitinga o nga pūtau uaua ngohengohe i roto i te whakatinanatanga o te kinase kingi-a-te-moki-a-te-p38 (MAPK) me te mea hiko-aukati (HIF) -1alpha me te whai muri mai o te hehe oxygenase-1 (HO-1) .

Kua pakuhia te waikawa o te waipiro o te phenffe ester hei he anti-carcinogenic, anti-inflammatory, me nga āhuatanga immunomodulatory. Ko te CAPE hoki ka whakakore i te whakaurutanga o HIV-1. Ko nga tohu anti-inflammatory kua whakaarohia he tika ki te whakakore i te ara o te lipoxygenase o te waikawa o te waikawa o te arachidonic e CAPE. Kua whakaatu ano hoki nga akoranga i te CAPE kia kaha ki te whakakore i te ahuatanga o te whakawhitinga karihi NF kappa B, he matatini pūmua e whakahaere ana i te tuhi o te DNA. Ko te waikawa o te Caffeic Phenethylester he kaipatu i te ODC me Tyrosine Kinase

Te waikawa waikawa phenethyl ester (Caffeic acid) (104594-70-9) Mahinga o te Mahi

Ko te waikawa o te phenffe ester te waipiro o te waipiro waipiro o te caffeic, ka poraka i te whakauru NF-κB i roto i te phorbol ester, ceramide, waikawa okadaic, me te waikawa hauora ma te aukati i te whakawhitinga o te p65 o te NF-κB ki te puranga. I roto i te raupapa o nga raina pūtau tumuaki, ko te phenéthethyl ester te hua o te koiora o te Caffeic me te EC50 o 1.76, 3.16, 13.7, me te 44.0 μM ki te kohi murino 26-L5, te muru B16-BL6 melanoma, te HT-1080 fibrosarcoma me te A549 huhu tangata nga raupapa waea tuhi adenocarcinoma. Ko te waikawa o te phenéthyl ester, ko te antioxidant kaha, ka kaha ki te whakaputa i ona huaketo anti-apoptotic i roto i nga ruma purapura miraka ma te whakakore i te hanganga ROS me te whakakore i te ngohe pakihi. Waihoki, ko te phenéthyl ester te caffeic acne te tohu tohu pro-inflammatory o LPS-whakaongaonga HSC, me te arotahi LPS-o te HSC ki te cytokines fibrogenic mā te aukati i te tohu NF-κB.

In vivo, Ko te waikawa o te phenéthyl ester (10 mg / kg, ip) ka whakakore i te tipu me te angiogenesis o nga pukupuku tuatahi i roto i te C57BL / 6 me te BALB / c e whakamahia ana ki te Leung o te carcinoma, te kaporeihana koroni, me nga kamera melanoma. Ko te waikawa o te phenethyl ester (5, 10, 20 mg / kg) ka whakaatu i nga hua o te immunomodulatory i roto i te ora i te whakaiti i te taimaha me te whakarau o te kaimoana me te rere.

Te whakamahinga o te waikawa waikawa phenethyl ester (Caffeic acid) (104594-70-9)

▪ Te taatai

▪ Aantiinflammatory

▪ Iimmunomodulator

▪ Motuhake NFKB

hua o Ko te waikawa waikawa phenethyl ester (Caffeic acid) (104594-70-9)

Ko te pëtereti caffeate he pühui i kitea i te propolis, he ranunga i whakaputaina e te pi. Ko te waipiro o te phenethyl ester (CAPE) ko te waikawa caffeic e taea te whai hua i roto i te tarai me te maimoatanga o nga mate inflammatory tae atu ki te urutai rhumatoid, te lupus erythematosus me te psoriasis, nga mate pukupuku me nga mate pukupuku me te mate pukupuku, me nga atu mate e puta mai ana i te raruraru pitihana. I tua atu, ka taea te whakamahi CAPE ki te hamani i te mate HIV i te wa e whakauruhia ai ki roto i te waihanga rongoa me tetahi taonga e pangia ai te urupare HIV. Ka taea hoki te whakamahi ki te anti-atherosclerotic, antioxidative, cardioprotective, anti-obesity me antimitogenic.

TE WHAKAMAHI ME TE KAUPAPA:

E Hokona ana tenei Pae Hei Whakamahi Rangahau anake. Tikanga o te Hoko Tono. Ehara i te mea mo te Tangata a te Tangata, kaore i te Akutaina, Whaiao, Whare Whainga Kaainga ranei.